COVID-19 Research

COVID-19 Studies

NameTypeFunderSponsorStatusApproval Date
HORIZON 2not availableJanssen Vaccines & Prevention B.V.Janssen Vaccines & Prevention B.V.In Setupnot available
CORONAVITInterventionalPHARMA NORD (UK) LIMITEDQueen Mary University of LondonClosednot available
CLARITYObservationalF. Hoffmann-La Roche Ltd; Hull University Teadhing Hospitals NHS TrustRoyal Devon and Exeter NHS Foundation TrustClosednot available
AERATORObservationalNIHR/UKRINorth Bristol NHS TrustOpennot available
ComFluCovInterventionalNIHR Central Commissioning Facility (CCF)UNIVERSITY HOSPITALS BRISTOL AND WESTON NHS FOUNDATION TRUSTOpen26-Mar-21
Comparing COVID-19 Vaccine Schedule Combinations - Stage 2 (Com-COV2)InterventionalDEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGYUniversity of OxfordIn Setup25-Mar-21
PROTECT VInterventionalLIFEARCCAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUSTOpen17-Mar-21
HEAL-COVID trialInterventionalNational Institute for Health Research (NIHR)CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUSTIn Setup17-Mar-21
Children & young people with Long Covid (CLoCk) studyObservationalNIHR / UKRIGREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUSTIn Setup10-Mar-21
OCTAVEnot availableNIHR / UKRIUniversity of BirminghamOpen01-Mar-21
A phase II study of a candidate COVID-19 vaccine in children (COV006)BothNIHR Central Commissioning Facility (CCF)not availableOpen17-Feb-21
Study of the safety of & response to a COVID-19 vaccine in pregnancyInterventionalJanssen-Cilag LtdJanssen-Cilag LtdIn Setup17-Feb-21
SPIKE-1InterventionalLIFEARCCancer Research UKOpen01-Feb-21
CO@h patient experience study (V1.0)ObservationalNIHRUniversity College LondonOpen29-Jan-21
SG016 Home StudyInterventionalnot availableSynairgen Research LimitedClosed13-Jan-21
A Randomized, Double-blind, Placebo-controlled Phase 2a Study to Evaluate a
Range of Dose Levels and Vaccination Intervals of Ad26.COV2.S in Healthy
Adults Aged 18 to 55 Years Inclusive and Adults Aged 65 Years and Older and
to Evaluate 2 Dose Levels of A
Interventionalnot availableJanssenOpen13-Jan-21
Non-inferiority study comparing immunogenicity against COVID-19 of VLA2001
with [ACTIVE COMPARATOR]
Interventionalnot availableValnevaIn Setup13-Jan-21
Com-COV: Comparing COVID-19 Vaccine Schedule CombinationsInterventionalDepartment for Business, Energy and Industrial StrategyUniversity of OxfordClosed13-Jan-21
COVID-19 Vacc Maternal ImmunisationInterventionalPfizer Inc.Pfizer Inc.In Setup13-Jan-21
CoVLPInterventionalMedicagoMedicagoIn Setup21-Dec-20
COVID-CNSObservationalMRC / UKRIUniversity of LiverpoolOpen21-Dec-20
PRONTOBothNIHRUniversity of LiverpoolOpen08-Dec-20
CCP-Cancer UKObservationalCLATTERBRIDGE CANCER CHARITY; NIHR / UKRITHE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUSTOpen06-Nov-20
SARS-COV-2 Virus Vaccine (VLA2001) against COVID-19InterventionalValnevaValnevaClosed29-Oct-20
STORM CHASERInterventionalAstraZenecaAstraZenecaClosed19-Oct-20
ADAPT-Sepsis TrialInterventionalNIHRUniversity of ManchesterOpen19-Oct-20
Phase III trial of inhaled anti-viral (SNG001) for SARS-CoV-2InterventionalSynairgen Research LimitedSynairgen Research LimitedOpen14-Oct-20
RECAPObservationalOxford team: UKRI. Imperial team: Community Jameel (philanthropic) fundImperial College LondonOpen14-Oct-20
PROVENTInterventionalAstraZenecaAstraZenecaClosed09-Oct-20
Characterisation of COVID-19 long-term immune responseObservationalMedical Research CouncilUniversity of BristolClosed01-Oct-20
A Phase 3 COVID-19 Vaccine StudyInterventionalJanssen-Cilag LtdJanssen-Cilag LtdClosed28-Aug-20
A trial to evaluate SARS-CoV-2 Recombinant Nanoparticle vaccineInterventionalNOVAVAX, INC.NOVAVAX, INC.Closed28-Aug-20
COVID-19 Infection SurveyObservationalOffice for National StatisticsUniversity of OxfordOpen20-Aug-20
COVID-19 Germ Defence ImplementationInterventionalNIHR/UKRIUniversity of BristolClosed10-Aug-20
NHS CHECKObservationalNIHR/UKRIKing's College LondonClosed05-Aug-20
CoMMinSObservational/InterventionalNIHR/UKRIUniversity of BristolOpen05-Aug-20
UK-REACHObservationalNIHR/UKRIUniversity of LeicesterOpen20-Jul-20
TraCK: Transmission of COVID-19 in KidsObservationalAction Medical ResearchImperial College of Science, Technology and MedicineOpen16-Jul-20
Humoral Immune Correlates for COVID19InterventionalNIHR/UKRIRoyal Papworth Hospital NHS Foundation TrustOpen01-Jul-20
UK Coronavirus Immunology Consortium (CIC)ObservationalNIHR/UKRIUniversity of BirminghamOpen01-Jul-20
PHOSP-COVIDObservationalNIHR/UKRIUniversity of LeicesterOpen01-Jul-20
COVID-HEARTObservationalnot availableLeeds Teaching Hospitals NHS TrustClosed04-Jun-20
C-MORE Capturing MultiORgan Effects of COVID-19ObservationalNIHR/UKRIUniversity of OxfordOpen04-Jun-20
VIVALDIObservationalDepartment of Health and Social CareUniversity College LondonOpen02-Jun-20
BASIL+BothNIHR Central Commissioning Facility (CCF)Tees, Esk and Wear Valleys NHS Foundation TrustOpen28-May-20
BASIL-C19InterventionalNIHRTees, Esk and Wear Valleys NHS Foundation TrustClosed28-May-20
REPROVIDEInterventionalNIHRUniversity of BristolOpen28-May-20
COVAC 1InterventionalNIHR/UKRIImperial College LondonClosed20-May-20
SIREN - SARS-COV2 immunity and reinfection evaluationObservationalPublic Health EnglandPublic Health EnglandClosed18-May-20
CATALYSTInterventionalnot availableUniversity of BirminghamClosed11-May-20
TACTIC-RInterventionalEly Lilly and Company; Alexion PharmaceuticalsCambridge University Hospitals NHS Foundation TrustOpen11-May-20
DEFINEInterventionalnot availablenot availableSuspended11-May-20
COG-UK HOCIInterventionalUK Research and Innovation (UKRI)University College LondonOpen11-May-20
OSCARInterventionalGlaxoSmithKlineGlaxoSmithKlineClosed07-May-20
MERMAIDS - ARIObservationalEuropean CommissionUniversity of OxfordOpen07-May-20
FALCON C-19ObservationalNIHR/UKRIManchester University NHS Foundation TrustOpen04-May-20
RAPTOR C-19ObservationalNIHR/UKRIUniversity of OxfordOpen04-May-20
FALCON C-19 (Workstream B)ObservationalNIHR / UKRIManchester University NHS Foundation TrustOpen04-May-20
Investigating a Vaccine Against COVID-19 (COV002)InterventionalNIHR/UKRIUniversity of OxfordClosed30-Apr-20
STOP-COVID19InterventionalInsmed IncUniversity of DundeeClosed21-Apr-20
ACCORDInterventionalBERGENBIO ASUNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUSTOpen21-Apr-20
Neonatal complications of coronavirus disease (COVID-19)ObservationalNIHRUniversity of OxfordOpen21-Apr-20
Virus WatchObservationalNIHR/UKRIUniversity College LondonOpen18-Apr-20
Pregnancy and Neonatal Outcomes in COVID-19ObservationalNIHR/UKRIImperial College of Science, Technology and MedicineOpen18-Apr-20
RECOVERY - Respiratory SupportInterventionalDepartment of Health and Social CareUniversity of WarwickOpen13-Apr-20
DeVENTInterventionalEuropean CommissionImperial College of Science, Technology and MedicineOpen13-Apr-20
CANCOVIDInterventionalNovartisNovartisClosed06-Apr-20
RUXCOVIDInterventionalNovartisNovartisClosed06-Apr-20
ILIAD 7InterventionalRevImmuneRevImmuneOpen06-Apr-20
What's the STORYObservationalNIHR/UKRIUniversity of OxfordOpen06-Apr-20
Repair of ARDS by Stromal Cell Administration (REALIST)InterventionalPublic Health Agency for Northern Ireland; Wellcome TrustBelfast Health & Social Care TrustOpen02-Apr-20
GenOMICCObservationalWellcome TrustNHS LothianOpen02-Apr-20
Coronavirus infection in immunosuppressed childrenObservationalBritish Paediatric Allergy, Immunity and Infection GroupUNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUSTClosed02-Apr-20
DIAMONDS SEARCHObservationalEuropean CommissionImperial College of Science, Technology and MedicineOpen02-Apr-20
SARS-CoV-2 infectionInterventionalSYNAIRGEN RESEARCH LIMITEDSYNAIRGEN RESEARCH LIMITEDClosed30-Mar-20
COPCOV trialInterventionalWellcome TrustUniversity of OxfordClosed30-Mar-20
REMAP-CAPInterventionalEuropean CommissionUniversity Medical Centre Utrecht (Netherlands)Open27-Mar-20
Adaptive COVID-19 Treatment Trial (ACTT)InterventionalNational Institutes of Health (NIH), United StatesUniversity of Minnesota (USA)Closed27-Mar-20
A study to evaluate TCZ in patients with severe COVID-19 PneumoniaInterventionalF. Hoffmann-La Roche LtdF. Hoffmann-La Roche LtdClosed26-Mar-20
5774 Safety & Antiviral Activity of Remdesivir for moderate COVID-19InterventionalGilead Sciences IncGilead Sciences IncClosed25-Mar-20
5773 Safety and Antiviral Activity of Remdesivir for severe COVID-19InterventionalGilead Sciences IncGilead Sciences IncClosed25-Mar-20
The PRIEST StudyObservationalNIHRSHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUSTClosed20-Mar-20
FLU-CATs : Evaluation and refinement of pandemic influenza community
assessment tools
ObservationalNIHRUniversity of LiverpoolOpen20-Mar-20
UKOSS: Pandemic Influenza in PregnancyObservationalNIHRUniversity of OxfordOpen20-Mar-20
A phase I/II trial of a candidate COVID-19 vaccine (COV001)InterventionalNIHR/UKRIUniversity of OxfordClosed11-Mar-20
RECOVERY trialInterventionalNIHR/UKRIUniversity of OxfordOpen11-Mar-20
PRINCIPLEInterventionalNIHR/UKRIUniversity of OxfordOpen11-Mar-20
Rapid development of manufacturing processes for future production of
adenovirus-vectored COVID19 vaccine at million-dose scale
Pre-clinicalNIHR/UKRIUniversity of Oxfordnot available11-Mar-20
nCoV: Developing CoV-bnMABs for therapy of highly pathogenic coronaviruses
including SARS-CoV-2
Pre-clinicalNIHR/UKRInot availablePossible pre-clinical study11-Mar-20
Repurposing FDA-Approved Drugs for Treatment of 2019-nCoV-induced DiseasePre-clinicalNIHR/UKRIQueens University Belfastnot available11-Mar-20
Clinical Characterisation Protocol (CCP) for Severe Emerging InfectionObservationalWellcome TrustUniversity of OxfordOpen24-Jan-20

Datasource:- NIHR

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